No, just no.
Match the cartridge to the game.
I’m sure a 223 77 gr in the vitals would kill large plains game, but what about less than ideal angles? Bullet blowup if it strikes a rib or the shoulder and doesn’t penetrate to the vitals? Need for a followup shot at a quartering animal?
On the other hand, I do think reasonable hunting calibers in the medium bore range are more similar than we appreciate. Since they all kill by tissue destruction and blood loss, it takes a large change to result in a significant change in on game performance. Is a 130 gr 6.5 monometal really that much worse than a 165 gr 30 cal? I’m skeptical. However, a 143 gr lead core vs a 220 gr? That’s enough of a difference to matter. And 6.5 130 gr monometal vs a 300 gr 375? That is suitable for different classes of game imo.
Match the cartridge to the game.
I’m sure a 223 77 gr in the vitals would kill large plains game, but what about less than ideal angles? Bullet blowup if it strikes a rib or the shoulder and doesn’t penetrate to the vitals? Need for a followup shot at a quartering animal?
On the other hand, I do think reasonable hunting calibers in the medium bore range are more similar than we appreciate. Since they all kill by tissue destruction and blood loss, it takes a large change to result in a significant change in on game performance. Is a 130 gr 6.5 monometal really that much worse than a 165 gr 30 cal? I’m skeptical. However, a 143 gr lead core vs a 220 gr? That’s enough of a difference to matter. And 6.5 130 gr monometal vs a 300 gr 375? That is suitable for different classes of game imo.