Any reason not to use a 350 grain .375 bullet for buffalo

[Hornedfrogbbq]

My home built .375 Weatherby does 2889 ft/s with a 300gr. I chronographed it. Long barrel. I throated it for a 350 and still left 3/8" of freebore. I've yet to load some 350's. Want to try them. Not sure what velocity I could get....maybe 2750 ft/s? That would be a real hammer. To date, it does so well with 300gr that I've not varied from that. Don't even intend to look at 270's. I just figured I'd run only 300's in it and that's that. But you guys have me thinking about 350's again

Jim, depending on how far you are trying to push them, you MIGHT even think about slowing that bullet down. It seems like I keep hearing (and I honestly know roughly nothing) that you want to be in a range of 2100 (and not under 2000) to 2300fps at point of impact.

I am 100% sure there are others on here that know more on this than I.

 

[375Fox]

I sure hear alot about the greatness of the Woodleigh hydro bullets but i don't believe anyone is commercially loading them right now...i could be wrong. I know Mark Haldane almost requires use of a Swift A Frame for the first shot because they are shooting in herds and don't want over-penetration. I think the last time I heard he will pay if it over-penetrates and injures another buff. If you use anything else, it's on the hunter.

The woodleigh hydro has acted as I expect from a solid. I shot buffalo center of chest and we found bullet under skin on back leg. Adjacent swift is from a zebra. There are a lot of good solid choices, but the woodleigh hydros feed really smoothly in my rifle.