100% agreed with
@sestoppelman,
@DOC-404,
@Kopskoot and @
Red Leg. 300 gr soft nose lead core did not become the standard reference at random. Surely, hundreds of thousands of buff died over the last 100 years verifying the appropriateness of the recipe...
Will bigger/faster do it too? Obviously yes! 400 gr .416, 500 gr .470, etc. come to mind...
Will 350 gr .375 do it too? Well... depends... As already noted by @
sestoppelman if your double shoots 6" groups at 50 yd with them, or if they punch paper sideways as noted by @
Kopskoot, most of us would probably stick to the 300 gr regulation load...
I notice that the 350 gr Norma loads fly at 2,175 fps at 50 yd and barely 2,050 fps at 100 yd, so the speed issue noted by
@Kopskoot is very real if the slug were a TSX (or other mono-metal?). In Norma's 350 gr case, however, they use Woodleigh softs and Woodleigh FMJ, so speed is not as critical.
Here is one more aspect that has not been discussed yet: all other considerations remaining equal, increasing the weight of the ejecta (bullet + powder) by 10% increases recoil by 20%. Conversely, a 10% lower speed will counteract and reduce recoil by 20%. So, going to 350 gr at 2,300 fps instead of 300 gr at 2,550 fps increases ejecta weight by 18% and reduces speed by 10%. Logically, one should expect an increase of recoil of 15%. This will not be an issue for some/most, but could it be for others?
On DG, there is no such thing as too dead, so this is where it seems that high weight retention mono-metal (and A Frame) deliver "added performance for same weight" over lower weight retention (older) soft nose lead bullets (including Nosler Partition that shed their front core). Sticking to 300 gr with a mono-metal up-guns the .375. A very, very sound approach as noted by
@Red Leg.
However, a growing number of folks (I am one of them) have started questioning whether "same performance with lower weight" is not a viable path? If indeed the performance is what it needs to be, and going mono-metal increases performance, then the same question logically asked by @
DOC-404 applies: why? (I purposefully teased the africahunting.com community with the provocative question of reducing bullet weight by the 30% that the Partition typically looses -
https://www.africahunting.com/threads/can-plains-game-a-frames-or-tsx-bullets-be-30-lighter.45537/ - to see what Brothers in Arms thought, and while we seem to all agree that 30% might be a bridge too far, it looks like a lot of us are comfortable with shooting mono-metal 10% lighter than lead core bullets).
So, to me, the question would be: will a .375 H&H 270 gr mono-meta do the same job and recoil less, hence be more shootable for most folks? (and increase the universality of the .375 by making it flatter shooting still).
And to further confuse the issue (LOL), I will hasten to add that I left the .375 bandwagon in favor of the .416 bandwagon when CZ finally "resurrected" the field-grade .416 Rigby, and that, anyway, I hunt buff with a Kreighoff .470 NE double. The rationale (?) to the .416 madness being that if there is a genuine point (?) about up-gunning the .375 to 350 gr bullets, then I guess that 400 gr .416 are even better. The rationale (?) to the .470 madness being that I just like the 'romance' of the big double...
PS: but I still have a .375 H&H and probably 5 or 6 boxes of Federal Premium 300 gr Nosler Partition for it. Some day, one of my sons will love it. The other will get the .416 R. Both guns will do the job if we have done our job of making sure that safari hunting is still a possibility for them...