As someone who has practiced reloading with a few designs (and actually beaten other practicing folks head to head) I would opt for the Ruger #1 over the 1885 High Wall, the Sharps, the Encore, and the NEF.
I found the break actions slower because of the ergonomics involved with opening the action putting me so far out of position for the remount and subsequent shot. The shotgun trigger on the NEF is annoying and the opening button seems like it should be on the opposite side of the hammer for best utility under time. The Encore/Contender has a good trigger, but then one has to deal with a captive extractor that must be manually cleared of the round unless you've made a rimmed cartridge choice, but even then you cannot reliably count on the "cowboy shuck" to clear a round with any substantial chamber pressure. I've had success with the Encore action in the field with multiple shots during an opportunity. I feel the tactical reload approach offers the best economy of motion. By this I mean breaking the gun with the firing hand and then reaching for a fresh cartridge between the index and middle fingers. The thumb and forefinger pull the spent case away from the action and discard it. Then the fresh cartridge is inserted and drive home with the thumb as the firing hand begins to close the action. I used an Encore pistol in the demonstration so as not to block the ammunition grab stroke. I believe the rifle is faster as the range of motion is reduced in the presentation. For your viewing pleasure I present both methods as best I could present them after a few repetitions to groove them in.
Tactical Reload vs.
Standard Reload
For those with safety concerns please observe that dummy rounds were utilized for this demonstration:
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I would opt for the Ruger #1 over the High Wall or Sharps because the tang safety is much faster than a hammer in my opinion. In the case of the Sharps the hammer must be cocked before the ejection stroke to prevent the firing pin from bending. In the case of the High Wall the hammer is cocked during the ejection stroke which is handy for follow on shots, but I wouldn't choose to have to cock it for the first shot. In all of the falling block actions I would choose an action mounted shell caddy for improved reload speed. I would endeavor to keep the rifle on the shoulder and tilt it as needed to facilitate ejection and loading.