I disagree with one statement you made Matt "The 450 Rigby is likely a great cartridge but the only history it has behind it is the Rigby name." I had considered a 500 Jeffery or a 505 Gibbs but the article that Karl Stumpfe wrote about the 450 Rigby convinced me that this is what I wanted. He uses it fairly extensively with great effect.
One of the owners of a hunting store I used to work at had a 505 Gibbs and loved it.
I almost bought a 500 Jeffery but my hesitation was the cartridge's rebated rim. A few articles I had read from hunters returning from African hunts where the cartridges had failed to extract due to extractors "jumping" the rim kinda didn't sit well. Not good when your quarry would've taken great pleasure in stomping you into a greasy spot or enjoying you as dinner!
To each his own when it comes to making decisions. Some like this, some like that. Whatever one chooses...feel comfortable with that choice otherwise you won't enjoy it (no were not including alcohol filled one nighter's in this discussion people. Suddenly I hear several dismayed moans of regret)
I like the 450 Rigby and 404, Witold likes the 404, some like the 458 Lott, or 416 Rigby, Matt likes calibres with very large holes!
Great thing; or sad thing depending on point of view, about the passion for hunting: "A lifetime of discussions but not enough life to discuss them!"