Let me know what you have. Thanks!
It depends, on who are you (financially)
I am safari hunter on a budget. With two safairs in PG, and planning some more.
I will never shoot dozens of buffalo and elephants. If I get one of each it will be great!
So, I can shoot a buffalo, or at the best an elehant cow. Plus occasional safari on PG in south africa or namibia,
From such perspective, bolt action 375 H&H for a client is more then enough. So I have zkk 602 in 375.
It will be ok for you as well.
On the other hand, if you can afford, and if you will have multiple safaris on premium game such as elephant, buffalo, rhino, and plains game, roan, sable, bongo, mountain nyala, etc ... and if you will be hunting: tanzania, camerun, Mosambigue, ethiopia, zambia, for other top premium plains game, then other inventory may be interseting, as money is no object.
In that case, bolt actions: 338 win mag, 300 win mag, 375 HH, 416 rigby, plus double rifles for DG, at close range: in 40+ caliber, starting with heym and kreighoff, and may have a look at holland and holland, rigby, westley richards, purdey.
You want economic, bolt action in 375 will cover it all.