To summarize, it is actually quite simple:
- 100% PG = .300
- 80% PG + 20% DG = .375
- 20% PG + 80% DG = .416
- 100% DG = .458
- Anything that presents itself = 1 Blaser R8 and 3 barrels...
This being said, four thoughts come to mind:
1) For PG there is nothing that a well placed and well constructed bullet from .25 caliber and up will not kill with a double lung shot from a perfect angle... Bigger & heavier bullets allow you to take shots from more difficult angles... Faster bullets give you a bit flater trajectory to not worry about ballistics between 0 and 300 yards...
2) For mixed PG and DG, on one end the 9.3x62 has always been in the run, but it lacks a bit of power and a bit of reach compared to the .375. On the other end, beware that the .416 hits noticeably harder ... on both ends! Too many people show up in Africa with a .416 they are afraid of and cannot shoot well, when they would have been perfectly well served, and much happier with a .375...
3) By the time you go for elephant, which is ultra specialized, you will likely have the desire and the "African bug" for a "stopper" caliber of .45+, but there is nothing that the .375 will not do with a good monolithic solid or a good TSX or AFrame...
4) By the time you have 3 or 4 Win 70 Safari Express in the safe, but can only take two at a time to Africa, you will have spent about the same money you would on a R8 Pro and 3 or 4 barrels and you will have nowhere near the flexibility. Many of us have been there and done that... Ask
Red Leg,
Philip Glass,
dchamp,
BeeMaa,
Opposite Pole, and many others ... and yes, me too... If you want the ability to take 3 calibers in one TSA max size & weight compliant rifle case, there is simply no other option...