I think 375Fox has it exactly right. I took 200 grain AccuBonds for my .300 Win Mag on.my last trip. All bullets passed through and the animals all did the "bang flop" or took just a couple of steps. The PG ranged from a small impala ewe up through a big waterbuck bull. If I had wanted another zebra or an eland, the bullets would have been fine. Would I have used a standard 180 grain Win, Rem or Fed? Not as long as I had a choice. I don't want an animal to suffer, and an animal hit and lost is an animal you pay for.In my opinion yes. Bonded bullets give predictable performance and penetration on bone on shoulder shots on eland, kudu, zebra, and larger PG. You are giving up some performance on smaller game like springbok, impala, duiker where premium bullets don’t expand as well, but I’d take predictable performance over bullets that have opportunity to fragment and give varying results. The vitals on African game are further forward than North American game and correct shot placement is on the shoulder not behind the shoulder.