Nice rifle! I can vouch that the 416rem will put buff and other big critters down no problems. 400gr swift A frames and 400gr barnes solids at 2500fps will do the trick. If you are a handloader and have a chronograph run both bullets at the same velocity and they will shoot pretty much to the same POI at 50 and 100yds. The barnes solids will need less powder and be a very compressed load. word of caution work up to that velocity and see if your gun can handle the pressures without stuck case issuses and test them in the heat of the day too.