A very interesting discussion. As a school boy many years ago I often dreamt of going to Africa. And finally in 2013 I managed to get to Namibia for a plains game hunt. After the hunt we went to Windhoek to do a bit of shopping and I thought it would be a good idea to go to the firearms shops to see what was popular for dangerous game rifles and what they carried for ammunition, in the event that I may some day return for a Cape Buffalo hunt, and considering the possible loss of ammunition during my transit. What I discovered, that in 2013, the common DG rounds to be found were 375 H&H, 416 Rigby, 404 Jeffrey, 458 Win Mag, 458 Lott, 500 Jeffrey, 505 Gibbs and the traditional double ammo 470 NE. But what was interesting was there were no 416 Rem, 416 Ruger (not sure if it was in production yet) or 375 Ruger on the shelves. Based on that I thought that if I was to return for DG hunt, I would choose one of the calibers that was most likely to be available in the area of the hunt. When I returned home I found a 416 Rigby in CZ 550 at one of our dealers and promptly purchased it, mounted a trijicon 1-4 DG scope and scoured the gunshops for any and all 416 Rigby brass and bullets for reloading. For 2018 I have made plans to go back, this time for an old Duggaboy, taking my son along for his first plains game hunt. Just an interesting observation regarding ammunition availability in Namibia, it's not quite like North Amertica. Something to maybe consider.
The problem with Africa is "No one has developed a vaccine that eliminates the desire to return."