Buy what you want and what makes you happy. I have a .470 NE, a .500 Jeffery, 2 .458 Lotts, a .416 Taylor, a .416 RM, and .470 Capstick, and I have a .404 Jeffery being built, and looking to build a .475 A&M Mag. I will never use them all, but it’s what I want. Not sure why people are asking you why you want them or trying to dissuade you. Hell, get them all.
Of the three you listed, I would go with .500 Jeffery. I have one in CZ 550 and have kicked around the idea of selling it. In my limited experience, I think dies and brass would be easier to get for the .500 Jeffery.
whatever you decide, shoot it and have fun with it.