Shooters Calculator and Hornady's ballistic calculator show a 50 yard zero and a 100 yard zero, with a 1.5" sight height and fired at 2500 fps, with no more than a 0.1" separation in ballistic arc at any distance from 0 - 100. I even set up the calculation on Shooters Calculator in 5 yard increments.
You'd have to get down to the MV I get out of my 45-70 with 405 gr or heavier at around 1600 fps to get any appreciable separation in arc for 50 vs 100 yd zero.
Even at 200 yards, whether 50 or 100 yard zero, the arc difference is still quite a bit smaller than the diameter of the projectile.
I worked up some 308 loads for both my sons' 308 Wins, 180gr Speer Grand Slam, about the same BC as 300 gr TSX, and right at 2500 fps, maybe 2525. Dead nuts on at 50 with that load was also dead nuts on at 100. And I did test that load at both 50 and 100, and got the results predicted by the ballistic calculators
If the BC is the same, and the MV is the same, then the ballistic arc is the same. And under 100 yards, BC isn't even relevant.
I've used both of those calculators pretty extensively for long range shooting, I find them both utterly reliable out to around 400 yards, and still close enough to true beyond that I was rarely off by more than .2 mrad, give or take a little.
But all that said, there's nothing like getting out to the range and confirming it.
If you're THAT concerned about a 5 or 10 yard shot being an inch+ high, then go with low rings for glass with a 24mm objective.