The only Remington 700 actions I own are varmint calibers and long-range calibers, including clones and I have several. Clones (many very good) is about your only option for a varmint or long-range rifle or an older 700 that has been "blueprinted". For plains game in Africa where the risk of a dangerous game encounter would be low, they likely would be fine! I use Model 70 CF or Dakota 76's with great success. Good Mauser actions including some old military 98s can be made into great rifles. The
CZ 550 and the South African Vektor actions are excellent to build a true African Dangerous/Big game rifle on. And, IMHO the Rolls Royce of big CF actions for a true magnum Dangerous Game rifle is the Granite Mountain action!
The 700 and its clones are not and never will be Dangerous Game actions/rifles to trust your life on!
That being said I personally hunt DG with a double rifle and a Custom Model 70 or Dakota as backup.
However, this year in Uganda I took a rifle for plains game that was one of several my late brother and I built as "ultralight mountain rifles" in the 80s. After his death in 2007 I retired this old battle hardened 300 Wby that is an aggressively lightened mag length Remington 700. with an early Kevlar Brown Precision stock and a laser bored break (designed and made by my Aeronautical engineer brother). Originally sporting a Leupold 2.5-8 in control rings at 6.5# now having a Leica 2.5-15x50 at 7.0#. This rifle has been in and out of a horse scabbard at least 1000x and taken 1-5 elk annually, Ibex, Aoudad, Caribou, Moose, Brown & black bear, Moral Stag in Mongolia, 2 other Stag species, 4 sheep species and many others in its 21ys prior to retirement.
Out of retirement it was off to Uganda in March. Using my beloved Swift A-frames (200gr) at a very mild 2825fps I was able to take 9 plains species (8 were one shot kills).
Of all the guns I've owned it is one of my most prized.