Unfortunately I have no experience with your overseas powders, only our locally produced South African powders, but if you had some of them I could give you plenty of loads from 350gr bullets up to 550gr.
My every day carry load for when Im out in the bush bumping into elles, buff and lions is 70gr of S335, under a 550gr Dzombo monolithic solid.
This load gives me 2100f/s and 1inch groups at 40m (thats open sights, shooting freehand), which is more then adiquate for what I need. (I use my Lott for a charge stopper, not long range hunting)
The 550gr Dzombo gives increadible penetration, even on elles.
I changed my front sight yesterday, from an 8mm fibre optic to a 9mm fibre optic, and had to bench it to check everything was still where it needs to be. Rifle still shoots beautifully, but all I can say is... Ouch!
HB