HDY 154 ideal for longer range deer and the Nos 175s for deer and bear. IMR 4350 was made for the 757 and 06 sized cases. What ranges do you intend to shoot? What part of USNY? For the 150s and 160s book max is 48 and 46 gr (so 47ish) and 45 gr for the 175. Seating depth will determine accuracy, though you can't go wrong starting with a factory std COAL. Even that 175 at 2550+ fps (4350) is good to well beyond 300 yds AND its SD (penetrating power) is precisely the same as a 220 gr bullet out of a .30 cal.
If you're not going to encounter any big bear, the 150ish gr is fine (the Nos PT is a better terminal performer than the others, however.) I really like my 757 AI. Loading up a bunch of 175s this summer for black bear with the son in the Fall (using my AI and his SAUM.) You'll find the 154 will outshine the 175 at distance (less drop, increased V and E) but the 175 will be a better performer when the bullet strikes (again suggested at <300, but run a ballistic calculator and you'll find it's likely good to 500 with such a good BC-0.520.) Nobody's going to shoot a 600-<900 lb black bear by me at more than 300 yds (let alone 50-150 with the ground cover they prefer.) Deer are another proposition altogether, out in the farmlands...If longer shots on deer, considering working up separate loads for each bullet and simply record the scope adjustments necessary to dial from one to another (likely a simple elevation adjustment.) You may find that the 150s are 3" high at 100 and the 175 is closer to dead-on (in which case-no adjustments are required in the bear vs. deer scenario.) Good luck! The loads below were chosen, as the V approximates same of max book loads using IMR 4350 (which is often the most accurate powder for the 757 case.)
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