I hunted Cape Buffalo and other game in Zimbabwe in 2021 and finished with a plains game hunt in Pearston, East Cape, South Africa. I used my Krieghoff Classic 5 in .470 NE with my hand loaded 500 grain Barnes TSX for the buffalo and for a sable in South Africa. We left my wife and a tracker in the bush and the PH and I stalked the Buff, who had moved around and ended up about 50-60 yards from my wife and the tracker, but facing away from her. I took a broadside shot at about 40 yards and the Buff wheeled around and started running right toward my wife and the tracker. Fortunately, the buff dropped within 30 yards of them. The Sable stood for 30 seconds after the shot, did not take a step and dropped where shot. The other plains game in South Africa were all taken with my Blaser in .375 H&H with 250 grain Barnes TTSX loaded by Choice Ammo in Colorado. Exceedingly accurate and deadly. With the exception of a Waterbuck who ran about 50 yards, all other animals shot with the Barnes TTSXs either dropped to the shot or took a few steps and fell over. My Black Wilderbeest was taken at 364 yards off sticks and took 3 or 4 steps and also dropped. I left a plastic unmaked box of the Choice Ammo .375s with my PH and, when I returned this year, he told me of clients using their camp rifle in .375 H&H to hunt Cape Buffalo. Two one shot kills with well placed broadside shots. They were under the impression that the .375s were 300 grain but they were not. Speaks volumes of the capability of Barnes 250 gr .375 TTSX and the importance of well placed shots.