I've owned 3 over the years, a Sabi at 10 3/4 lb everyone loved to shoot it, had a Vector SSB action, about 5 years later picked up a 98 500Jeffery, felt stunning had to have it.. but around 9.4lb it kicked hell out of me with all my tries at mild loads/powders around 2220fps and 535grainers. Was about to weight it up a lb... and along came a nice London Guns, Melbourne 500Jeffery, beautiful rifle at 10.5lb.. Loved this for a few years and truely did a great job.. Alas moved it on needed the $$s and not being carried much in 2018. Getting older, less muscles and 404 / 416 fine for me.
But in saying that I almost bought another in Feb 2020, price was right.. a Sabi 98... but CV19 put a stop to that work requirement.
After all that... I suggest 11lb loaded, no scope.. much enjoyment to be had. Buffalo are hit so hard wether 2250 or 2300 or 2250fps doesn't matter.