Once you find your recoil tolerance (mine is a 570g bullet at 2300 fps in an 11 lb 500 Jeffery) even a little bit more recoil seems to really get my attention. I'm thinking of loading them "down" to 2150 fps too
An opinion on the original posters question, I felt like my .500 Jefferey CZ 550 recoiled about 60-70% more than my 450/400.
Good comments by all;
I listen to the men with real experience here. Big Bore rillfes are a passion for me, and I practice regulary to one day fulfill my dream of a Cape Buffalo in Southern Africa.
My CZ 550 weighed 5.2 kg with sling and ammo.
I immediately learned my recoil tolerance when I fired the first 2 shots of Kynoch 535 grain at 2400 fps. The other 3 rounds went with the sale of the gun. They were a beast to shoot.
My master plan was to load 570 grains at 2150, like the .500 Nitro Express.
I fired maybe 50 rounds, over a couple months and realized it was too much recoil, as my accuracy was poor after 4 or 5 shots. I had clearly defined, my recoil tolerance.
I have two 450/400's, a double and a Ruger #1. The double is no problem, and am using faster burning Reloder 15, just a nice big push, and back on target quickly.
The Ruger Number 1 takes some concentration, as it delivers recoil differently.
Stock fit, actual Recoil Velocity play a part.
I shoot my Whitworth .458 Win Mag with full power 500 grains at 2150, and handle this the best, 15-20 rounds off sticks.
What did I learn?
Stock fit is crucial; The Whitworth fits me very well.
I read long ago, from an British officer ( can't remember his name) that was a weapons developer, and big game hunter in Africa and India.
He stated most men can stand recoil velocity up to 17 pounds feet per second, just right where I am with my double 450/400.
I really liked the CZ .500 Jeffery, but knowing my limitations, sold it to a member here for his buffalo hunt.
By all means, if you can shoot a .500 Jeffery, maybe with a .500 NE load as well, do so before you buy.