For whitetail deer, I think you will find that the heavier .416s are kind of a waste. They punch through deer from any angle like they are punching through a sheet of paper. They will definitely expand if the deer are close (especially the Woodleigh, it has become one of my favorite bullets), but the 410 is is probably limited to 2,100-2,200fps in a .416 Taylor (depending on your barrel length) without running the ragged edge of pressure and getting short brass life. By my calculations, they are below the threshold for reliable expansion at 100 yards (1,900fps is probably the lowest for reliable expansion in my experience) and you will likely not get full expansion at 50 yards because there isn't much resistance in a deer. If you don't plan on shooting farther than 100 yards, it will definitely kill, but if your looking for a bullet to perform on animals that size, The 340 grain Woodleigh Weldcore PP is fantastic. They open up reliably, hold together and can be pushed out of your Taylor at 2,600 fps with less recoil! Still massive overkill for deer, but if you want to you use your Taylor on deer, that's the Woodleigh bullet I would recommend.