Old wisdoms die hard; opinions often last a lifetime...
This is a recurring question that has been answered many times, but it is always worth revisiting...
There are opinions, and there are facts. Some opinions have been expressed already, so I will focus on facts.
What made the reputation of the 180 gr (actually the 200 gr) .30-06 load in Africa were older technology cup & core bullets that typically fragmented upon impact and penetrated with various weights of fragments. Progressing to the first "premium" bullet, the Nosler Partition, things started to get a little more predictable. The front core typically expanded quite explosively during impact and shaved off during the first couple inches of penetration, and the deep penetration was accomplished by the rear core, which typically represent 60 to 70% of the Nosler Partition weight. In so many words, a 180 gr NP typically penetrates with 180 gr x 70% retained weight = 126 gr penetrator.
It follows that for a given caliber, .30 for example, a 130 gr TTSX that retains 95% of its weight will penetrate just as deep as a 180 gr Partition, and typically deeper that a 180 gr cup & core bullet (and will generally create a wider wound channel).
I have not tested the .30-06 per se, but I have tested extensively the .300 Wby magnum on large PG and my experience is that:
- the .30 165 gr TTSX invariably penetrates deeper and kills faster than the 180 Nosler Partition;
- the 1.30 80 gr TTSX does not provide any better results that the 165 gr TTSX; both punch through and exit on all large PG, never mind small PG;
- the .30 165 gr TTSX shoots meaningfully flatter than the 180 gr TTSX;
- the .30 165 gr TTSX recoils meaningfully less than the 180 gr TTSX;
and actually:
- the .30 130 gr TTSX punches through large PG just the same (including wildebeest, Kudu, etc.), therefore it penetrates just as deep, and, if anything, it kills even faster than the 165 or 180 gr TTSX likely due to more consistent hydrodynamic shock;
- the .30 130 gr TTSX shoots a lot flatter than both the .30 165 gr and 180 gr TTSX;
- the .30 130 gr TTSX recoils significantly less than both the .30 165 gr and 180 gr TTSX.
If data is relevant to one's mind, this all makes sense as a .30 130 gr that retains 95% weight penetrates with essentially the same weight (124 gr) as a .30 180 gr that retains 70% weight (126 gr), not to mention that it flies a lot faster.
Old wisdoms die hard; opinions often last a lifetime; and hard facts are often not well known, so most folks continue to shoot 180 gr in their .30 or .300, but those who have shot the TTSX extensively will tell you that you can advantageously go 1 or even 2 bullet weights down the scale. I do...
This being said, opinions clearly carry more weight than facts in ammo sales, because I observe that Weatherby first stopped offering the 130 gr TTSX in factory .300 Wby loads, and then a few years later even stopped offering the 165 gr TTSX in factory .300 Wby loads, and now only offer the 180 gr TTSX. They will freely admit that this is due to sales volume, not performance. They load what folks buy. I regretted not having stocked up on the 130 gr TTSX load, and I bought 10 boxes of 165 gr TTSX load when I realized they were discontinuing it. That will last me 10 to 15 years as I only shoot the TTSX Weatherby loads on game and use the cheaper Interlock Weatherby loads for practice...
The 168 gr load carries a mystique because it was traditionally the "sniper" load in .30 caliber, but there is exactly zero field difference between 168 gr and 165 gr. Then of course, for those who do not reload, factories dictate the choices, I do not think that Barnes offers any other option than the 180 gr in TTSX .30-06. But I you load your own, you can confidently explore what shoots best (accuracy, trajectory, recoil) for you among the .30 TTSX from 180 gr down to 130 gr, through 168, 165 and 150 gr. All will kill just the same any PG that walks the earth, and the heavier ones will up-gun the .30-06 into Eland territory with a careful shot, and will lengthwise the lungs from the rear up in follow up shots on large PG; this last point being the valid argument for preferring 165 gr to 130 gr on large PG.
PS: as to how many shots it takes to kill, it all depends where the shots land... which is the main argument for limiting shooting distance, even from quad sticks...