One of my favorite gun writers, Ross Seyfried, was a pretty accomplished gentleman. Really knowledgeable gun writer, experienced big game hunter who liked the big bore rifles and handguns. He was 1981 IPSC World Champion Johannesburg, South Africa, done with a moderately customized Pachmyr 1911, the last one to perform this with a fairly standard pistol before the advent of highly modified race guns with red dots taking over.
Ross was also a PH in Africa from 1979-1989, United Safari Zambia, working with PH’s Cotton Gordon, Mike Cameron, Ray Sparrow and Hugo Seia. His primary rifle used to back up hunting clients was a Remington 700 KS 416 Rem Mag synthetic stock with the bolt modified with a Sako extractor.
I won’t lie, my personal preferences are CRF Winchester Model 70’s and Brno ZKK-602/CZ 550 for DG but I wouldn’t hesitate to use a Remington 700 with the bolt modified with an M16 style extractor and putting the necessary rounds down range to insure reliability for DG hunting. As an aside, I’ve put over 200 rounds through my Remington Custom Shop 375 RUM with the standard unmodified extractor without issue.
From what I’ve read so far on AH, most favor CRF Mauser style bolt action rifles, factory or custom, and more than a few really like their Blaser R8’s and of course the double rifle folks. Those who like the Remington 700 for DG seem to be fewer but it’s performed fine with those who’ve used it.