Oh, and I forgot to add... My second choice is a gun under construction at this time... a .280 Remington Ackley Improved. I chose it because as I note in my missive under "What calibre to bring on a single gun hunt," like the .35 whelen, it provides a considerable amount of flexibility it round selection.
For the first time I've ever seen, there is a commercially available "Ackley Improved" offering. Two, in fact. Nosler produces two .280 Rem AI rounds; 140 and 160 grain, using the Accubond bullet. Both provide 7mm Remington Magnum velocity/energy levels in a smaller package. This is possible because of new powders now available. Meanwhile, the standard .280 Remington rounds provide notably more power than the .270 Winchester in a variety of offerings, while often matching the .30-06. And like the 7mm-08 vs it's parent the .308 Winchester, it's a little flatter shooting than the .30-06 while retaining energy a little better at longer ranges. Finally, you can hand-load them to 7x57 Mauser levels. The latter is one of my favorite cartridges, and I have a rifle in that chambering as well.
So, my choice, for what it's worth, would be the .280 Remington Ackley Improved and the .35 Whelen.
NOTE: For those of you who might not be familiar with the "Ackley Improved" line, they're improved versions of the parent cartridges, in that the taper is taken out of the case and the shoulder moved forward and steepened. This increases the powder capacity versus the parent. They're, technically speaking, wildcats, however, you can still use factory ammo in the rifle, so you kind of get two rifles in one. I fact, although in some offerings AI cases can be bought, most are fireformed using factory ammunition of the standard cartridge. The advantage is higher velocities providing a quasi-magnum capability and, for handloaders, longer case life. The disadvantage, from what I've read, is a greater chance of a misfeed while rapidly chambering a follow on round over the parent cartridge due to the steep shoulder.