I am looking at trying to get a 375 for hunting buffalo, hippo, etc… the problem I have is I shoot left handed and left handed bolt guns are typically hard to find. In my looking the 375 Ruger is coming up more than the 375 H&H in left handed options. For those that have experience with either of these cartridges is one significantly better than the other? Pros/Cons of each as far as hunting performance goes. Any and all input would be appreciated. Thanks