I just loaded up a test batch of Woodleigh 160, using H4350 for those. The plan is to go to the range Sunday morning.
More than a few guys are getting in the 2700 fps range with 140s. That's fine as far as it goes, and if you can get there safely, more power to you. But with the degree of precision I'm getting from Hornady, and what I'm hoping to get with the Woodleighs, I'm happy at 2500 with what I have, will be happy at 2400 with the 160s and sub-MOA. The only thing for which I'd feel undergunned in NA with the 160s is the griz.
When I hunt, I like to hunt. I save the long range stuff for my target 308.