Beautiful new Winchester (Miroku) 1886 .50-110 completely done up by Turnbull.
It is the takedown version and has a 24" barrel with a 1-20" twist to stabilise heavy bullets.
I was doing preliminary load development this weekend and was getting clover leaf groups at 50 m using cast NOE 520 gr (with my alloy lubed and sized) FNGC sized to .512" and enouph Bench Mark to do a comfortable 1968 fps.
It is originally a black powder round, typically shooting either a 300 gr in the 1600 fps range or a 450 at 1400 fps or so. With good BP (3fg), I have chronographed 330 gr at 1740 in my rifle. My duplex loads are doing 1860 fps.
With modern loads, in a strong action, I would probably put it in about the same general class as the 458 Win Mag. It's a 50 cal of course and shoots similar weight bullets at similar velocities.
All being equal, it doesn't have the sectional density of the 45 cal, but makes up for it in frontal area.