I find the 243 neither fish or foul it's to big for small game and to little for medium game.
I like all 25s from 25/20 up to the weatherby.
I designed my own 25 based on a 303 British case necked down to 25caliber, blown out almost straight, the shoulder has been moved forward and is 35 degrees and the neck is now .257 inches long. I call it the 25/303 Epps Newton improved
It launches a 115grain nosler combined technology silver tip at 3,300+ fps and a 100grain Barnes TTSX at 3,600+ fps. These are actual chronoed velocities.