I shot this herfard years ago with my marlin md. 95 in 45-70 with a 405 gr hard cast GC bullet at 1900 fps, one shot between the eyes and the bullet was recovered in the spine 21" back of the head. I forget the retained weight, but I think it was around 300 grs. so that bullet went thru the complet skull front to back and 21"of spine. your 50-110 should do better with the right bullet